Genome analysis of two newly emerged potato late blight isolates shed lights on pathogen adaptation and provides tools for disease management.
Identifieur interne : 000155 ( Main/Exploration ); précédent : 000154; suivant : 000156Genome analysis of two newly emerged potato late blight isolates shed lights on pathogen adaptation and provides tools for disease management.
Auteurs : Fan Zhang [République populaire de Chine] ; Han Chen [République populaire de Chine] ; Xinjie Zhang [République populaire de Chine] ; Chuyun Gao [République populaire de Chine] ; Jie Huang [République populaire de Chine] ; Lv Li [Oman] ; Danyu Shen [République populaire de Chine] ; Luyao Wang [Oman] ; Chong Huang [République populaire de Chine] ; Wenwu Ye [République populaire de Chine] ; Xiaobo Zheng [États-Unis, République populaire de Chine] ; Yuanchao Wang [République populaire de Chine] ; Jack Vossen [Pays-Bas] ; Suomeng Dong [République populaire de Chine]Source :
- Phytopathology [ 0031-949X ] ; 2020.
Abstract
Phytophthora infestans, the causal agent of the Irish Potato Famine in the 1840s, is one of the most destructive crop pathogens that threaten global food security. Host resistance (R) genes may help to control the disease, but recognition by through the gene products can be evaded by newly emerging isolates. Such isolates are dangerous as they may cause disease outbreaks under favorable conditions. However, our lack of knowledge about adaptation in these isolates jeopardizes an apt response to resistance breakdown. Here we performed genome and transcriptome sequencing of HB1501 and HN1602, two field isolates from distinct Chinese geographic regions. We found extensive polymorphisms in these isolates, including gene copy number variations, nucleotide polymorphisms, and gene expression changes. Effector encoding genes, which contribute to virulence, show distinct expression landscapes in P. infestans isolates HB1501 and HN1602. In particular polymorphisms at multiple effectors required for recognition (Avr loci) enabled these isolates to overcome corresponding R gene based resistance. Although the isolates evolved multiple strategies to evade recognition, we experimentally verified that several R genes such as R8, RB, and Rpi-vnt1.1 remain effective against these isolates and are valuable to potato breeding in the future. In summary, rapid characterization of the adaptation in emerging field isolates through genomic tools inform rational agricultural management to prevent potential future epidemics.
DOI: 10.1094/PHYTO-05-20-0208-FI
PubMed: 33026300
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leoson40@163.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University, 70578, plant protection, Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University, 70578, plant protection, Nanjing</wicri:regionArea><wicri:noRegion>Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; shendanyu@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Luyao" sort="Wang, Luyao" uniqKey="Wang L" first="Luyao" last="Wang">Luyao Wang</name><affiliation wicri:level="1"><nlm:affiliation>Chinese Academy of Agricultural Sciences Agricultural Genomes Institute at Shenzhen, 441191, Shenzhen, Guangdong, China; wangluyao2015@gmail.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Chinese Academy of Agricultural Sciences Agricultural Genomes Institute at Shenzhen, 441191, Shenzhen, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Chong" sort="Huang, Chong" uniqKey="Huang C" first="Chong" last="Huang">Chong Huang</name><affiliation wicri:level="3"><nlm:affiliation>National Agro-Tech Extension and Service Center, Beijing, China; huangchong@agri.gov.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>National Agro-Tech Extension and Service Center, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; 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smdong@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33026300</idno><idno type="pmid">33026300</idno><idno type="doi">10.1094/PHYTO-05-20-0208-FI</idno><idno type="wicri:Area/Main/Corpus">000073</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000073</idno><idno type="wicri:Area/Main/Curation">000073</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000073</idno><idno type="wicri:Area/Main/Exploration">000073</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genome analysis of two newly emerged potato late blight isolates shed lights on pathogen adaptation and provides tools for disease management.</title><author><name sortKey="Zhang, Fan" sort="Zhang, Fan" uniqKey="Zhang F" first="Fan" last="Zhang">Fan Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2018202005@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; hanchen@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xinjie" sort="Zhang, Xinjie" uniqKey="Zhang X" first="Xinjie" last="Zhang">Xinjie Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2018102036@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Gao, Chuyun" sort="Gao, Chuyun" uniqKey="Gao C" first="Chuyun" last="Gao">Chuyun Gao</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2017202005@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; jiehuang@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Li, Lv" sort="Li, Lv" uniqKey="Li L" first="Lv" last="Li">Lv Li</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; leoson40@163.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University, 70578, plant protection, Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University, 70578, plant protection, Nanjing</wicri:regionArea><wicri:noRegion>Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; shendanyu@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Luyao" sort="Wang, Luyao" uniqKey="Wang L" first="Luyao" last="Wang">Luyao Wang</name><affiliation wicri:level="1"><nlm:affiliation>Chinese Academy of Agricultural Sciences Agricultural Genomes Institute at Shenzhen, 441191, Shenzhen, Guangdong, China; wangluyao2015@gmail.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Chinese Academy of Agricultural Sciences Agricultural Genomes Institute at Shenzhen, 441191, Shenzhen, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Chong" sort="Huang, Chong" uniqKey="Huang C" first="Chong" last="Huang">Chong Huang</name><affiliation wicri:level="3"><nlm:affiliation>National Agro-Tech Extension and Service Center, Beijing, China; huangchong@agri.gov.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>National Agro-Tech Extension and Service Center, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; wwye@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University, Plant Pathology Department, Nanjing, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Nanjing Agricultural University, Plant Pathology Department, Nanjing</wicri:regionArea><wicri:noRegion>Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; xbzheng@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, China; ycwang@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Vossen, Jack" sort="Vossen, Jack" uniqKey="Vossen J" first="Jack" last="Vossen">Jack Vossen</name><affiliation wicri:level="1"><nlm:affiliation>Wageningen UR, Plant Breeding, Droevendaalsesteeg 1, Wageningen, Netherlands, 6708 PB; jack.vossen@wur.nl.</nlm:affiliation><country wicri:rule="url">Pays-Bas</country><wicri:regionArea>Wageningen UR, Plant Breeding, Droevendaalsesteeg 1, Wageningen, Netherlands</wicri:regionArea><wicri:noRegion>Netherlands</wicri:noRegion></affiliation></author><author><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, China; smdong@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author></analytic><series><title level="j">Phytopathology</title><idno type="ISSN">0031-949X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Phytophthora infestans, the causal agent of the Irish Potato Famine in the 1840s, is one of the most destructive crop pathogens that threaten global food security. Host resistance (R) genes may help to control the disease, but recognition by through the gene products can be evaded by newly emerging isolates. Such isolates are dangerous as they may cause disease outbreaks under favorable conditions. However, our lack of knowledge about adaptation in these isolates jeopardizes an apt response to resistance breakdown. Here we performed genome and transcriptome sequencing of HB1501 and HN1602, two field isolates from distinct Chinese geographic regions. We found extensive polymorphisms in these isolates, including gene copy number variations, nucleotide polymorphisms, and gene expression changes. Effector encoding genes, which contribute to virulence, show distinct expression landscapes in P. infestans isolates HB1501 and HN1602. In particular polymorphisms at multiple effectors required for recognition (Avr loci) enabled these isolates to overcome corresponding R gene based resistance. Although the isolates evolved multiple strategies to evade recognition, we experimentally verified that several R genes such as R8, RB, and Rpi-vnt1.1 remain effective against these isolates and are valuable to potato breeding in the future. In summary, rapid characterization of the adaptation in emerging field isolates through genomic tools inform rational agricultural management to prevent potential future epidemics.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33026300</PMID><DateRevised><Year>2020</Year><Month>10</Month><Day>07</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0031-949X</ISSN><JournalIssue CitedMedium="Print"><PubDate><Year>2020</Year><Month>Oct</Month><Day>07</Day></PubDate></JournalIssue><Title>Phytopathology</Title><ISOAbbreviation>Phytopathology</ISOAbbreviation></Journal><ArticleTitle>Genome analysis of two newly emerged potato late blight isolates shed lights on pathogen adaptation and provides tools for disease management.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1094/PHYTO-05-20-0208-FI</ELocationID><Abstract><AbstractText>Phytophthora infestans, the causal agent of the Irish Potato Famine in the 1840s, is one of the most destructive crop pathogens that threaten global food security. Host resistance (R) genes may help to control the disease, but recognition by through the gene products can be evaded by newly emerging isolates. Such isolates are dangerous as they may cause disease outbreaks under favorable conditions. However, our lack of knowledge about adaptation in these isolates jeopardizes an apt response to resistance breakdown. Here we performed genome and transcriptome sequencing of HB1501 and HN1602, two field isolates from distinct Chinese geographic regions. We found extensive polymorphisms in these isolates, including gene copy number variations, nucleotide polymorphisms, and gene expression changes. Effector encoding genes, which contribute to virulence, show distinct expression landscapes in P. infestans isolates HB1501 and HN1602. In particular polymorphisms at multiple effectors required for recognition (Avr loci) enabled these isolates to overcome corresponding R gene based resistance. Although the isolates evolved multiple strategies to evade recognition, we experimentally verified that several R genes such as R8, RB, and Rpi-vnt1.1 remain effective against these isolates and are valuable to potato breeding in the future. In summary, rapid characterization of the adaptation in emerging field isolates through genomic tools inform rational agricultural management to prevent potential future epidemics.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Fan</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2018202005@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Han</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; hanchen@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xinjie</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2018102036@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Chuyun</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; 2017202005@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huang</LastName><ForeName>Jie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; jiehuang@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Lv</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China; leoson40@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shen</LastName><ForeName>Danyu</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University, 70578, plant protection, Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; shendanyu@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Luyao</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Chinese Academy of Agricultural Sciences Agricultural Genomes Institute at Shenzhen, 441191, Shenzhen, Guangdong, China; wangluyao2015@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huang</LastName><ForeName>Chong</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>National Agro-Tech Extension and Service Center, Beijing, China; huangchong@agri.gov.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ye</LastName><ForeName>Wenwu</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; wwye@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zheng</LastName><ForeName>Xiaobo</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University, Plant Pathology Department, Nanjing, United States.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China; xbzheng@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yuanchao</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, China; ycwang@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vossen</LastName><ForeName>Jack</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Wageningen UR, Plant Breeding, Droevendaalsesteeg 1, Wageningen, Netherlands, 6708 PB; jack.vossen@wur.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Suomeng</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University Department of Plant Pathology, 214176, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing, Jiangsu, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, China; smdong@njau.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>10</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Phytopathology</MedlineTA><NlmUniqueID>9427222</NlmUniqueID><ISSNLinking>0031-949X</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Analytical and theoretical plant pathology</Keyword><Keyword MajorTopicYN="N">Disease Control and Pest Management</Keyword><Keyword MajorTopicYN="N">Mycology</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>10</Month><Day>7</Day><Hour>12</Hour><Minute>9</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>10</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>10</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33026300</ArticleId><ArticleId IdType="doi">10.1094/PHYTO-05-20-0208-FI</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Oman</li><li>Pays-Bas</li><li>République populaire de Chine</li><li>États-Unis</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Zhang, Fan" sort="Zhang, Fan" uniqKey="Zhang F" first="Fan" last="Zhang">Fan Zhang</name></noRegion><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><name sortKey="Gao, Chuyun" sort="Gao, Chuyun" uniqKey="Gao C" first="Chuyun" last="Gao">Chuyun Gao</name><name sortKey="Huang, Chong" sort="Huang, Chong" uniqKey="Huang C" first="Chong" last="Huang">Chong Huang</name><name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name><name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><name sortKey="Zhang, Xinjie" sort="Zhang, Xinjie" uniqKey="Zhang X" first="Xinjie" last="Zhang">Xinjie Zhang</name><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name></country><country name="Oman"><noRegion><name sortKey="Li, Lv" sort="Li, Lv" uniqKey="Li L" first="Lv" last="Li">Lv Li</name></noRegion><name sortKey="Wang, Luyao" sort="Wang, Luyao" uniqKey="Wang L" first="Luyao" last="Wang">Luyao Wang</name></country><country name="États-Unis"><noRegion><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name></noRegion></country><country name="Pays-Bas"><noRegion><name sortKey="Vossen, Jack" sort="Vossen, Jack" uniqKey="Vossen J" first="Jack" last="Vossen">Jack Vossen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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